If you’ve been craving something creamy, savory, and totally keto-approved, this Keto Garlic Mushroom Chicken Casserole will change your weeknight dinners forever. Juicy chicken, sautéed mushrooms, garlic, and a silky cheese sauce come together into a one-dish wonder that’s high in protein, low in carbs, and unbelievably satisfying.
It’s one of those recipes that feels indulgent — but actually keeps you on track. No flour, no pasta, no guilt. Just clean, simple comfort food that fuels your body and fits your macros perfectly. 🍽️
- ✔️ 35g+ protein per serving
- ✔️ Ultra creamy and low in carbs
- ✔️ Easy to make, meal prep–friendly
- ✔️ Family-approved, budget-friendly dinner
- ✔️ Freezes and reheats perfectly
Storytime: When I first switched to low-carb, I missed creamy casseroles the most. So I turned my favorite Sunday chicken bake into this high-protein, low-carb masterpiece. I tested it three times until it was just right — thick sauce, no watery mushrooms, and that golden top that makes you want to dive right in. It’s now a weekly meal prep essential at my house!
Ingredients
| Ingredient | Amount |
|---|---|
| Chicken breasts or thighs (boneless) | 1 ½ lbs |
| Cremini or button mushrooms, sliced | 2 cups |
| Fresh garlic, minced | 4 cloves |
| Heavy cream | 1 cup |
| Cream cheese | 2 oz |
| Grated Parmesan cheese | 1/3 cup |
| Shredded mozzarella (optional topping) | ½ cup |
| Butter or olive oil | 2 tbsp |
| Fresh spinach (optional) | 1 cup |
| Salt, pepper, paprika | to taste |
Choosing the Best Ingredients
Chicken: Use boneless, skinless chicken thighs for juicy, tender results — or chicken breast if you want to keep fat lower. Either works beautifully here.
Mushrooms: Cremini (baby bella) mushrooms give the casserole a rich, earthy flavor and stay firm when baked. Avoid canned mushrooms — they release too much water.
Cream Cheese & Heavy Cream: The power duo that makes keto casseroles creamy and decadent. For a lighter version, use ¼ cup Greek yogurt instead of cream cheese.
Parmesan & Mozzarella: For that stretchy, cheesy top layer — and extra flavor without carbs!
Pro Tips for the Perfect Keto Casserole
- Cook mushrooms first to remove moisture — no soggy casseroles here!
- Use a hot skillet to brown the chicken before baking; it locks in flavor.
- Mix cream cheese and cream on low heat until smooth before combining.
- Let the casserole rest 10 minutes before serving — the sauce thickens perfectly.
- Add a handful of spinach or kale for extra fiber and micronutrients.
Pair this with Air Fryer Garlic Parmesan Potatoes for your non-keto guests, or a side of Mediterranean Baked Feta Eggs for a protein-packed brunch twist.
Step-by-Step Instructions
- Preheat & Prep: Set oven to 400°F (200°C). Grease a medium casserole dish with butter or avocado oil.
- Sear the Chicken: In a skillet over medium-high heat, add oil and brown chicken 2–3 minutes per side. Remove and set aside.
- Sauté Mushrooms & Garlic: In the same pan, melt butter and sauté sliced mushrooms until golden (about 6–7 minutes). Add minced garlic and cook 30 seconds more.
- Make the Cream Sauce: Reduce heat to low. Add cream cheese and heavy cream, whisk until smooth. Stir in Parmesan, salt, and pepper. Simmer for 2–3 minutes until thickened.
- Combine: Layer chicken and mushrooms in casserole dish. Pour sauce evenly on top. Sprinkle with mozzarella if using.
- Bake: Bake uncovered for 20 minutes, or until bubbling and lightly golden on top.
Meal Prep & Reheat Tips
- Divide into 4 airtight containers for meal prep. Keeps up to 4 days in the fridge.
- Reheat in air fryer or oven for 5–8 minutes at 350°F for that fresh-out-of-oven texture.
- Freezes well for up to 2 months. Thaw overnight in the fridge before reheating.
Variations
- Extra Veggies: Add broccoli florets, zucchini, or cauliflower rice for volume and fiber.
- Spicy Kick: Stir in red pepper flakes or a touch of cayenne for heat.
- More Protein: Add diced bacon or shredded rotisserie chicken.
- Dairy-Light Version: Use coconut cream and nutritional yeast instead of dairy cheeses.
Nutrition Breakdown (per serving)
- Calories: ~430 kcal
- Protein: 37g
- Fat: 28g
- Net Carbs: 5g
FAQ
- Can I use rotisserie chicken? Yes! Just skip the searing step and reduce bake time to 15 minutes.
- Can I make this dairy-free? Swap cream for coconut cream and cheese for dairy-free alternatives.
- How do I keep it from getting watery? Sauté mushrooms well before baking to release all moisture.
- What sides go best? Try Garlic Butter Bread Rolls for family nights, or a green salad for a lighter meal.
Conclusion
This Keto Garlic Mushroom Chicken Casserole is everything you want from a low-carb dinner — creamy, comforting, and full of flavor without breaking your diet. It’s simple enough for busy weeknights, delicious enough for Sunday prep, and satisfying enough to make your keto lifestyle feel easy. Save it, make it, and keep it on repeat!
Craving more low-carb comfort? You’ll love Keto Garlic Parmesan Chicken — it’s crispy, creamy, and another fan-favorite in the ComfortFoodLite kitchen. 💛
Keto Garlic Mushroom Chicken Casserole
Ingredients
- 1 1/2 lbs chicken breasts or thighs boneless, skinless
- 2 cups mushrooms sliced
- 4 cloves garlic minced
- 1 cup heavy cream
- 2 oz cream cheese
- 1/3 cup Parmesan cheese grated
- 1/2 cup mozzarella optional topping
- 2 tbsp olive oil or butter
- 1 cup spinach optional
- to taste salt and pepper
Instructions
- Preheat oven to 400°F (200°C). Grease a casserole dish.
- Brown chicken in oil for 3–4 min per side; remove and set aside.
- Sauté mushrooms and garlic in butter until golden.
- Add cream, cream cheese, and Parmesan. Whisk until creamy.
- Layer chicken, mushrooms, and sauce in dish. Top with mozzarella.
- Bake 20–25 minutes until bubbly and golden.
